Detalhe da pesquisa
1.
ANGPTL8/betatrophin does not control pancreatic beta cell expansion.
Cell
; 159(3): 691-6, 2014 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-25417115
2.
The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3.
Proc Natl Acad Sci U S A
; 121(6): e2312291121, 2024 Feb 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38294943
3.
Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc Natl Acad Sci U S A
; 118(34)2021 08 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34404721
4.
Contribution of a genetic risk score to ethnic differences in fatty liver disease.
Liver Int
; 42(10): 2227-2236, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35620859
5.
Crystal structure of the human sterol transporter ABCG5/ABCG8.
Nature
; 533(7604): 561-4, 2016 05 26.
Artigo
Inglês
| MEDLINE | ID: mdl-27144356
6.
Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis.
Proc Natl Acad Sci U S A
; 116(19): 9521-9526, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31019090
7.
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.
N Engl J Med
; 378(12): 1096-1106, 2018 03 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29562163
8.
Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice.
Proc Natl Acad Sci U S A
; 115(6): E1249-E1258, 2018 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29358393
9.
Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance.
J Lipid Res
; 61(9): 1271-1286, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32646941
10.
PCSK9: From Nature's Loss to Patient's Gain.
Circulation
; 149(3): 171-173, 2024 01 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38227713
11.
PNPLA3, CGI-58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice.
Hepatology
; 69(6): 2427-2441, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30802989
12.
Patatin-like phospholipase domaincontaining protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets.
J Biol Chem
; 293(18): 6958-6968, 2018 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29555681
13.
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride.
Hepatology
; 67(6): 2182-2195, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29266543
14.
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.
Hepatology
; 66(4): 1111-1124, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28520213
15.
Hepatic ANGPTL3 regulates adipose tissue energy homeostasis.
Proc Natl Acad Sci U S A
; 112(37): 11630-5, 2015 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26305978
16.
ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance.
J Lipid Res
; 58(6): 1166-1173, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28413163
17.
Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins.
J Biol Chem
; 291(20): 10659-76, 2016 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-27013658
18.
HSD17B13 and Chronic Liver Disease in Blacks and Hispanics.
N Engl J Med
; 379(19): 1876-1877, 2018 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30403941
19.
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
Hepatology
; 61(1): 108-18, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24917523
20.
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis.
Proc Natl Acad Sci U S A
; 110(40): 16109-14, 2013 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24043787